Drug name: Triampur

Other names used:
Dyazide®
Maxzide®

Active Ingredients:
Hydrochlorothiazide (HCTZ) + Triamterene

Therapeutic actions: Triampur is a combine preparation that belongs to a group of medicines called diuretics or “water pills”. The medication exerts diuretic and hypotensive action.

Therapeutic effect of HCTZ is associated with interfering with the reabsorption of sodium, chloride, magnesium and water in distal nephron. HCTZ also inhibits the elimination of calcium ions and uric acid. As a result, Triampur increases the amount of salt and water which are removed by the kidney from the blood. This lowers blood volume making possible to reduce high blood pressure and help with water retention.

Hydrochlorothiazide always causes low potassium levels in the blood. However, Triamterene being potassium sparing water pill increases potassium levels. Thus, the combination of HCTZ and Triamterene contributes to the balance of potassium levels.

Indications: Triampur is indicated in the following conditions:
Controlling high blood pressure (hypertension)
Treating water retention (edema).

Contraindications and cautions: Triampur is contraindicated in the following conditions:
Anuria
Chronic kidney failure
Acute glomerulonephritis
Severe liver diseases
Hypovolemia
Pregnancy
Breastfeeding
High potassium levels(hyperkalemia)
Hypersensitivity to sulfanilamids

Necessarily talk with your doctor if you experience the following conditions:
Liver disease, including cirrhosis
Kidney failure
Bronchial asthma
Kidney stone disease
Diabetes
Systemic lupus erythematosus
Gout
Fluid problems
Electrolyte problems
Deficiency of folic acid
People under 18 years of age
Acidosis

Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Triampur will experience it or any other.
Digestive system: nausea, vomiting, diarrhea, stomach pain, dry mouth, thirst
CNS: tremor, drowsiness, tiredness, headache, spasms of the calf muscles
Cardiovascular system: increased heart rate, decreased blood pressure, disorder of the heart rhythm, tendency to faintness, acute liver failure
Metabolism: increased amount of nitrogen-containing substance in the blood, disorder of the water-electrolyte balance
Hematopoietic system: anemia, thrombocytopenia,
Skin allergic reactions: hives, rash, Quinke's edema, fever, anaphylactic reaction, severe inflammation of the blood levels, pulmonary edema
Other: jaundice, vision problems

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with Triampur, please read the information provided with Triampur or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Triampur. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.

Triampur may interact with the following medications:
ACE inhibitors
Angiotensin II receptor blockers
Corticosteroids
Laxatives
Nonsteroidal anti-inflammatory drugs(NSAID's)
Potassium-containing products

Water pills(spironolactone)
Blood thinners(warfarin)
Cardiac glycosides(digoxin)
Lithium preparations
Amiloride
Amphotericin B
Antifungal agents

Additional Information: DO NOT SHARE Triampur with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.